Potocka-Płazak K
Kliniki Geriatrii Akademii Medycznej, Krakowie.
Przegl Lek. 1992;49(4):123-7.
The effect of gradually increasing doses of catecholamines on the heart rate, arterial pressure and the left heart ventricle systolic time intervals has been studied in the group of 30 aged subjects (70 to 95 years old) and the control group aged 23 to 30 years. The initial resting QS2I, LVETI, PEPI, heart rate and diastolic pressure were similar in both groups studied whereas the chronotropic and inotropic response as well as the vasodilatation were weaker in the aged. The disturbed mechanisms of adaptation in the aged could be caused by limited response of the circulatory system to adrenalin secreted during the stress states.
在30名老年受试者（70至95岁）和23至30岁的对照组中，研究了逐渐增加剂量的儿茶酚胺对心率、动脉压和左心室收缩时间间期的影响。研究的两组受试者初始静息状态下的QS2I、LVETI、PEPI、心率和舒张压相似，但老年人的变时性和变力性反应以及血管舒张作用较弱。老年人适应机制紊乱可能是由于应激状态下循环系统对分泌的肾上腺素反应受限所致。
