Hawkins R A, Hoh C, Glaspy J, Choi Y, Dahlbom M, Rege S, Messa C, Nietszche E, Hoffman E, Seeger L
Department of Radiological Sciences, UCLA School of Medicine 90024.
Semin Nucl Med. 1992 Oct;22(4):268-84. doi: 10.1016/s0001-2998(05)80121-7.
Imaging and quantifying biochemical and physiological processes with PET clearly has major potential significance for all organ systems and many disease states. Although the full utility and potential of emerging new applications of PET in organs other than the heart and brain must be demonstrated in basic and clinical research studies, the rapidly accumulating aggregate experience in oncology in particular, and in other organ systems and disease states as well, indicates that PET is now truly becoming a modality of both clinical and investigative use for the body as a whole as well as for specific organ systems. Whole-body PET FDG imaging (Fig 9) illustrates the potential of biochemical imaging to map the distribution of cancer throughout the body. With the growing list of radiopharmaceutical and quantitative techniques applicable to cancer studies with PET, this field will continue to realize significant growth.
利用正电子发射断层扫描（PET）对生物化学和生理过程进行成像和定量分析，显然对所有器官系统和许多疾病状态都具有重大的潜在意义。尽管PET在心脏和大脑以外器官的新兴新应用的全部效用和潜力必须在基础和临床研究中得到证明，但特别是在肿瘤学领域，以及在其他器官系统和疾病状态方面迅速积累的总体经验表明，PET现在正真正成为一种用于全身以及特定器官系统的临床和研究工具。全身PET FDG成像（图9）展示了生物化学成像在描绘癌症在全身分布方面的潜力。随着适用于PET癌症研究的放射性药物和定量技术的不断增加，该领域将继续实现显著增长。
