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[正常及去势成年雄性大鼠垂体前叶核膜中5α-还原酶活性的定位]

[Localization of a 5alpha-reductase activity in the nuclear membranes of the anterior hypophysis of normal and castrated adult male rats].

作者信息

Ducouret B, Samperez S, Jouan P

出版信息

C R Seances Soc Biol Fil. 1977;171(3):639-43.

PMID:144004
Abstract

A 5alpha-reductase activity may be found in purified nuclei from anterior pituitary of intact or castrated male rats. When nuclear membranes are separated from nucleoplams this enzymic activity is recovered in nuclear membranes. Following 7 days of castration, the 5alpha-reductase activity in nuclear membranes is increased by 105 % with regard to the activity in nuclear membranes from intact animals.

摘要

在完整或阉割雄性大鼠的垂体前叶纯化细胞核中可发现5α-还原酶活性。当核膜与核质分离时,这种酶活性在核膜中得以恢复。阉割7天后,核膜中的5α-还原酶活性相对于完整动物核膜中的活性增加了105%。

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1
[Localization of a 5alpha-reductase activity in the nuclear membranes of the anterior hypophysis of normal and castrated adult male rats].[正常及去势成年雄性大鼠垂体前叶核膜中5α-还原酶活性的定位]
C R Seances Soc Biol Fil. 1977;171(3):639-43.
2
[Hormonal regulation of 5 alpha-reductase activity in anterior pituitary gland microsomes of the male rat].[雄性大鼠垂体前叶微粒体中5α-还原酶活性的激素调节]
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Nuclear RNA content and synthesis in anterior pituitary in intact, castrated and androgen sterilized rats.
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Neuroendocrinology. 1975;19(1):36-43. doi: 10.1159/000122423.
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Effect of castration on the smooth muscle cells of the internal sex organs of the rat: influence of the smooth muscle on the sympathetic neurons innervating the vas deferens, seminal vesicle and coagulating gland.去势对大鼠内生殖器官平滑肌细胞的影响:平滑肌对支配输精管、精囊和凝固腺的交感神经元的影响。
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Intercellular communication within the rat anterior pituitary gland: V. Changes in cell-to-cell communications as a function of the timing of castration in male rats.
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5alpha-reductase activity of genital and nongenital skin fibroblasts from patients with 5alpha-reductase deficiency, androgen insensitivity, or unknown forms of male pseudohermaphroditism.5α-还原酶缺乏症、雄激素不敏感或不明形式男性假两性畸形患者生殖器及非生殖器皮肤成纤维细胞的5α-还原酶活性。
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