Schaaf-Lafontaine N
C R Seances Soc Biol Fil. 1977;171(3):663-6.
The cytotoxic activity of lymphoid cells from mice bearing syngeneic sarcomas is increased when these cells are preincubated on heavily irradiated cells of the same tumours. This secondary stimulation is highest at the time when the cytotoxicity measured directly is relatively low. In consequence, whatever the age of the tumour, the level of cytotoxicity reached (35-45 %) cannot be increased further in normal conditions.
当携带同基因肉瘤的小鼠的淋巴细胞在相同肿瘤的重度照射细胞上预孵育时,这些细胞的细胞毒性活性会增加。这种二次刺激在直接测量的细胞毒性相对较低时最高。因此,无论肿瘤的年龄如何,在正常情况下达到的细胞毒性水平(35%-45%)都不能进一步提高。