[大鼠中缓激肽的前列腺素释放活性的抑制作用]
[Inhibition of the prostaglandin-liberating activity of bradykinin in the rat].
作者信息
Damas J
出版信息
C R Seances Soc Biol Fil. 1977;171(3):685-9.
PMID:144012
Abstract
In the rat, hydrocortisone, dexamethasone and chloroquine do not inhibit the hypotensive activity of arachidonic acid, which is due to endogenous prostaglandin synthesis. They reduce or suppress the secondary hypotensive phase induced by bradykinin. These substances inhibit the prostaglandin releasing activity of bradykinin but do not interfere with prostaglandin synthesis.
摘要
在大鼠中，氢化可的松、地塞米松和氯喹并不抑制花生四烯酸的降压活性，该活性归因于内源性前列腺素的合成。它们可减轻或抑制缓激肽诱导的继发性降压阶段。这些物质抑制缓激肽的前列腺素释放活性，但不干扰前列腺素的合成。
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