Rekhter M D, Andreeva E R, Andrianova I V, Mironov A A, Orekhov A N
Institute of Experimental Cardiology, Cardiology Res. Center, Moscow, Russia.
Tissue Cell. 1992;24(5):689-96. doi: 10.1016/0040-8166(92)90039-a.
Stellate cells hitherto accounted exclusively in the innermost elastic-hyperplastic layer were already reported to inhabit human aortic intima. The present paper shows that most of these cells are situated just beneath the endothelium. Stellate cells also appear in the deendothelialization-induced myointimal thickening of rabbit aorta. In the myointimal thickening these cells were revealed in the direct proximity to the endothelium. A conclusion is available that the previously demonstrated polymorphism of human aortic intimal cells may be reproduced in a simple experimental model, which gives new possibilities for the study of the cellular polymorphism in the vessel wall.
星状细胞以往仅见于最内层弹性增生层,现已报道其存在于人类主动脉内膜。本文表明,这些细胞大多位于内皮细胞下方。星状细胞也出现在兔主动脉去内皮化诱导的肌内膜增厚中。在肌内膜增厚处,这些细胞紧邻内皮细胞。由此可得结论,先前证明的人类主动脉内膜细胞的多态性可在一个简单的实验模型中重现,这为研究血管壁细胞多态性提供了新的可能性。