Brodskiĭ V Ia, Sarkisov D S, Aref'eva A M, Panova N V, Gvazava I G
Tsitologiia. 1992;34(3):17-22.
With general atherosclerosis, the ploidy of left ventricle myocytes in the hearts of patients that underwent infarction corresponds to the norm variation irrespective of the ventricle and heart weights. At heart diseases the myocyte nucleus ploidy is often much higher than the norm variability both in hypertrophied ventricles and in those with normal weight. An additional polyploidization is suggested that may occur at some natural ontogenetic periods of human development (in the childhood) during heart diseases both innate or spontaneously appearing at the particular time. Unlike, the myocardial hypertrophy in adults does not stimulate myocyte polyploidy.
在一般动脉粥样硬化情况下，发生梗死的患者心脏中左心室心肌细胞的倍性与正常变异相符，与心室和心脏重量无关。在心脏病中，无论是肥厚的心室还是重量正常的心室，心肌细胞核倍性通常都远高于正常变异范围。有人提出，在人类发育的某些自然个体发育阶段（儿童期），无论是先天性心脏病还是在特定时期自发出现的心脏病，都可能发生额外的多倍体化。与成人不同，成人的心肌肥大不会刺激心肌细胞多倍体化。
