Schröder J, Honer M R, Louw J P
J S Afr Vet Assoc. 1977 Jun;48(2):95-7.
Four experiments are described in which the efficacy of an experimental 5% injectable solution of rafoxanide was evaluated against various adult and immature helminths in cattle. Subcutaneous injection at a dosage of 3 mg/kg live mass resulted in the following reductions in mean worm burdens: adult Fasciola hepatica, 82,6%; adult Fasciola gigantica, 99,8% immature Paramphistomum microbothrium, 10,1% adult Haemonchus placei, 99,6%, third stage H. placei, 73,7%; adult Bunostomum phlebotomum, 99,8%; adult Oesophagostomum radiatum, 99,9%; and fourth stage O. radiatum, 76,9%. At 5 mg/kg live mass, rafoxanide solution was 97,5% and 99,2% effective against 8-week old F. gigantica and third stage H. placei respectively and at 7,5 mg/kg, 92,4% against 6-week old F. gigantica.
本文描述了四项实验，评估了一种5%的雷复尼特注射溶液对牛体内各种成虫和未成熟蠕虫的疗效。以3毫克/千克体重的剂量进行皮下注射，平均蠕虫负荷减少情况如下：肝片形吸虫成虫，82.6%；巨片形吸虫成虫，99.8%；微小双口吸虫未成熟虫体，10.1%；牛血矛线虫成虫，99.6%；牛血矛线虫第三期幼虫，73.7%；牛钩口线虫成虫，99.8%；辐射食道口线虫成虫，99.9%；辐射食道口线虫第四期幼虫，76.9%。以5毫克/千克体重注射时，雷复尼特溶液对8周龄巨片形吸虫和牛血矛线虫第三期幼虫的有效性分别为97.5%和99.2%，以7.5毫克/千克体重注射时，对6周龄巨片形吸虫的有效性为92.4%。
