Tien R D, Cardenas C A, Rajagopalan S
Department of Radiology, Duke University Medical Center, Durham, NC 27710.
AJR Am J Roentgenol. 1992 Dec;159(6):1287-90. doi: 10.2214/ajr.159.6.1442403.
Pleomorphic xanthoastrocytoma is a rare, usually benign brain tumor. This pleomorphic supratentorial tumor involves the leptomeninges and superficial cortex in young patients with seizures. The MR imaging features of this distinct tumor have not been reported. We describe the MR imaging findings in six patients with pathologically proved pleomorphic xanthoastrocytoma.
We retrospectively reviewed the MR images of six patients with pathologically proved pleomorphic xanthoastrocytoma. MR images were reviewed by two neuroradiologists. The pathologic slides of the tumors were reviewed by two neuropathologists. We also analyzed the patients' clinical features.
Most of the tumors were cortical based and isointense with gray matter on T1-weighted images and mildly hyperintense on T2-weighted images. All the masses enhanced with contrast material. Cystic components and gyriform and leptomeningeal enhancement were seen occasionally. The tumors occurred in the temporal lobes in four of the six patients. Three patients had seizures, and the other three had headaches.
Pleomorphic xanthoastrocytoma is a rare, usually benign, cortical-based mass that often enhances intensely with contrast material. The most common location is in the temporal lobes. Seizures and headaches are common clinical features. Familiarity with this lesion is important in the differential diagnosis of enhancing cortical-based masses.
多形性黄色星形细胞瘤是一种罕见的、通常为良性的脑肿瘤。这种多形性幕上肿瘤累及软脑膜和浅表皮质，好发于有癫痫发作的年轻患者。这种独特肿瘤的磁共振成像（MR）特征尚未见报道。我们描述了6例经病理证实为多形性黄色星形细胞瘤患者的MR成像表现。
我们回顾性分析了6例经病理证实为多形性黄色星形细胞瘤患者的MR图像。由两名神经放射科医生对MR图像进行评估。两名神经病理学家对肿瘤的病理切片进行评估。我们还分析了患者的临床特征。
大多数肿瘤位于皮质，在T1加权像上与灰质等信号，在T2加权像上轻度高信号。所有肿块均有强化。偶尔可见囊性成分以及脑回状和软脑膜强化。6例患者中有4例肿瘤位于颞叶。3例患者有癫痫发作，另外3例有头痛症状。
多形性黄色星形细胞瘤是一种罕见的、通常为良性的、位于皮质的肿块，通常强化明显。最常见的部位是颞叶。癫痫发作和头痛是常见的临床特征。熟悉这种病变对于强化的皮质肿块的鉴别诊断很重要。
