Braverman D Z, Morali G A, Patz J K, Jacobsohn W Z
Gastrointestinal Unit, Shaare Zedek Medical Center, Jerusalem, Israel.
Am J Gastroenterol. 1992 Nov;87(11):1591-3.
The monthly pattern of distribution of endoscopically diagnosed duodenal ulcer disease was evaluated for the years 1975-1989. A retrospective review of 3105 endoscopies performed for peptic disease was recorded and analyzed. Among them, 2020 endoscopies revealed duodenal bulb deformity, and 1035 revealed the presence of acute duodenal ulcer. Chi-square analysis of the data for goodness of fit revealed statistical differences for certain months. Slightly more patients with chronic deformity presented in June and November, whereas more patients with acute duodenal ulcer presented in July, November, and December (p < 0.001). The ratio of acute to chronic disease was nearly constant throughout the year. The Edwards chi 2 test for seasonal trends did not reveal any seasonality (p > 0.75). The differences observed in June-July and November-December, as compared with the rest of the year, were so small that they should not be relied upon for the clinical management of peptic disease.
对1975年至1989年期间经内镜诊断的十二指肠溃疡病的月度分布模式进行了评估。对3105例因消化性疾病进行的内镜检查进行了回顾性记录和分析。其中，2020例内镜检查显示十二指肠球部畸形，1035例显示存在急性十二指肠溃疡。对数据进行卡方拟合优度分析，发现某些月份存在统计学差异。6月和11月出现慢性畸形的患者略多，而7月、11月和12月出现急性十二指肠溃疡的患者更多（p<0.001）。全年急性与慢性疾病的比例几乎恒定。爱德华兹卡方季节性趋势检验未显示任何季节性（p>0.75）。与一年中的其他时间相比，6月至7月和11月至12月观察到的差异非常小，因此不应将其用于消化性疾病的临床管理。
