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草酸钙尿路结石形成机制的研究。III. 镁在草酸盐结石形成中的作用。

A contribution to the formation mechanism of calcium oxalate urinary calculi. III. On the role of magnesium in the formation of oxalate calculi.

作者信息

Berg W, Hesse A, Schneider H J

出版信息

Urol Res. 1976;4(4):161-7. doi: 10.1007/BF00262349.

DOI:10.1007/BF00262349
PMID:14432
Abstract

The influence of magnesium in vitro on the precipitation of calcium oxalate was investigated. Even at maximum physiological magnesium concentrations a litholytic effect could not be observed, but the retardation of the calcium oxalate crystallization caused by magnesium might be decisive for a reduction in calculi formation. The enlargement of the calcium oxalate crystals and aggregates caused by the retardation of crystallization, however, should be regarded as a contraindicating factor for Mg therapy in oxalate calculous disease. It is safe to say that high magnesium concentrations prevent the conversion into Whewellite of the calcium oxalate calculi substance primarily formed as Weddellite.

摘要

研究了镁在体外对草酸钙沉淀的影响。即使在最大生理镁浓度下,也未观察到溶石作用,但镁引起的草酸钙结晶延迟可能对减少结石形成具有决定性作用。然而,由结晶延迟导致的草酸钙晶体和聚集体的增大,应被视为草酸钙结石病中镁治疗的一个禁忌因素。可以肯定地说,高镁浓度可防止主要以二水草酸钙形式形成的草酸钙结石物质转化为一水草酸钙。

相似文献

1
A contribution to the formation mechanism of calcium oxalate urinary calculi. III. On the role of magnesium in the formation of oxalate calculi.草酸钙尿路结石形成机制的研究。III. 镁在草酸盐结石形成中的作用。
Urol Res. 1976;4(4):161-7. doi: 10.1007/BF00262349.
2
A contribution to the formation mechanism of calcium oxalate urinary calculi. II. In vitro experiments concerning the theory of the formation of Whewellite and Weddellite urinary calculi.草酸钙尿路结石形成机制的研究。II. 关于水草酸钙和二水草酸钙尿路结石形成理论的体外实验
Urol Res. 1976;4(4):157-60. doi: 10.1007/BF00262348.
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Influence of magnesium on the absorption and excretion of calcium and oxalate ions.
Eur Urol. 1986;12(4):274-82. doi: 10.1159/000472635.
4
A contribution to the formation mechanism of calcium oxalate urinary calculi. I. Stabilising urinary constituents in the formation of weddellite.草酸钙尿路结石形成机制的研究贡献。I. 稳定草酸钙二水合物形成过程中的尿液成分。
Urol Res. 1976 Nov 10;4(3):125-8. doi: 10.1007/BF00257168.
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Aspects of the influence of magnesium ions on the formation of calcium oxalate.镁离子对草酸钙形成的影响方面
Urol Res. 1981;9(4):157-61. doi: 10.1007/BF00264820.
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The effects of magnesium and pH on experimental calcium oxalate stone disease.
Invest Urol. 1969 Jan;6(4):412-22.
7
[Relation between calcium phosphates and calcium oxalates in urinary calculi].
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[Influence of oxianthraquinones on the crystallization of calcium oxalate and calcium phosphate: dissolution of calciumcontaining urinary calculi (author's transl)].[蒽醌类化合物对草酸钙和磷酸钙结晶的影响:含钙尿路结石的溶解(作者译)]
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[Morphological studies on the formation of oxalate stones (author's transl)].草酸盐结石形成的形态学研究(作者译)
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Crystaloptical and spectroscopical findings with calcium oxalate crystals in the urine sediment: a contribution to the genesis of oxalate stones.尿液沉渣中草酸钙晶体的晶体光学和光谱学研究结果:对草酸盐结石成因的贡献
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引用本文的文献

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Can Vet J. 2018 Dec;59(12):1305-1310.
2
Mechanism of urinary calcium regulation by urinary magnesium and pH.尿镁和pH对尿钙的调节机制。
J Am Soc Nephrol. 2008 Aug;19(8):1530-7. doi: 10.1681/ASN.2007091038. Epub 2008 Apr 30.
3
The effect of ions at the surface of calcium oxalate monohydrate crystals on cell-crystal interactions.一水合草酸钙晶体表面离子对细胞 - 晶体相互作用的影响。

本文引用的文献

1
Effects of extra magnesium intake in experimental production of urinary calculi.额外摄入镁对实验性尿路结石形成的影响。
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2
Production of calcium oxalate renal calculi in vitamin B6-deficient rats. Study of the influence of urine pH.维生素B6缺乏大鼠草酸钙肾结石的形成。尿液pH值影响的研究。
Lab Invest. 1960 Jan-Feb;9:7-27.
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The urinary excretion of oxalic acid and magnesium in oxalate urolithiasis.草酸钙结石症中草酸和镁的尿排泄情况。
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Aspects of the influence of magnesium ions on the formation of calcium oxalate.镁离子对草酸钙形成的影响方面
Urol Res. 1981;9(4):157-61. doi: 10.1007/BF00264820.
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Crystallisation of calcium oxalate dihydrate in normal urine in presence of sodium copper chlorophyllin.在叶绿酸铜钠存在的情况下,正常尿液中草酸钙二水合物的结晶。
Urol Res. 1982;10(4):173-6. doi: 10.1007/BF00255940.
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A contribution to the formation mechanism of calcium oxalate urinary calculi. I. Stabilising urinary constituents in the formation of weddellite.草酸钙尿路结石形成机制的研究贡献。I. 稳定草酸钙二水合物形成过程中的尿液成分。
Urol Res. 1976 Nov 10;4(3):125-8. doi: 10.1007/BF00257168.
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A contribution to the formation mechanism of calcium oxalate urinary calculi. IV. Experimental investigations of the intrarenal crystallisation of calcium oxalate in rabbit.对草酸钙尿路结石形成机制的贡献。IV. 兔肾内草酸钙结晶的实验研究
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Invest Urol. 1967 Nov;5(3):303-12.
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[Complex chemical basis of urinary calculogenesis].
Helv Med Acta. 1966 Dec;30(6):724-55.
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Oral magnesium intake and its effect on various urinary constituents in the prophylaxis of urolithiasis.口服镁摄入及其在预防尿路结石中对各种尿液成分的影响。
J Urol. 1966 Nov;96(5):812-5. doi: 10.1016/S0022-5347(17)63357-3.
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[Magnesium in the prevention of calcium oxalate urinary calculi].[镁在预防草酸钙尿路结石中的作用]
Z Urol Nephrol. 1965 May;58(5):341-4.
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The effects of magnesium and pH on experimental calcium oxalate stone disease.
Invest Urol. 1969 Jan;6(4):412-22.
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Control of crystallization in urine.
Am J Med. 1968 Nov;45(5):693-9. doi: 10.1016/0002-9343(68)90205-2.
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Magnesium and calcium oxalate solubility.草酸镁和草酸钙的溶解度
Invest Urol. 1971 Jan;8(4):386-90.
10
[Clinical and laboratory findings in 470 patients with calcilithiasis of the upper urinary tract].[470例上尿路结石患者的临床及实验室检查结果]
Urol Int. 1969;24(4):318-29. doi: 10.1159/000279631.