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对草酸钙尿路结石形成机制的贡献。IV. 兔肾内草酸钙结晶的实验研究

A contribution to the formation mechanism of calcium oxalate urinary calculi. IV. Experimental investigations of the intrarenal crystallisation of calcium oxalate in rabbit.

作者信息

Hienzsch E, Hesse A, Bothor C, Berg W, Roth J

出版信息

Urol Res. 1979 Sep;7(3):223-6. doi: 10.1007/BF00257209.

DOI:10.1007/BF00257209
PMID:505683
Abstract

Rabbits were given glyoxylic acid to induce intrarenal calcium oxalate crystal formation. The point of crystallisation in the renal tubule, the structure and the composition of the intrarenal crystals were studied. The initial crystallisation takes place in the proximal tubule. Calcium phosphate formation was excluded by microprobe examination. The comparison of the structures of the intrarenally formed crystals with those of Whewellite stones by scanning electron microscopy and the examination of isolated crystals by x-ray diffraction showed the intratubular crystals to consist of Whewellite.

摘要

给兔子注射乙醛酸以诱导肾内草酸钙晶体形成。研究了肾小管内的结晶点、肾内晶体的结构和组成。初始结晶发生在近端小管。通过微探针检查排除了磷酸钙的形成。通过扫描电子显微镜对肾内形成的晶体与水草酸钙结石的结构进行比较，并通过X射线衍射对分离出的晶体进行检查，结果显示肾小管内晶体由水草酸钙组成。

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1
A contribution to the formation mechanism of calcium oxalate urinary calculi. IV. Experimental investigations of the intrarenal crystallisation of calcium oxalate in rabbit.对草酸钙尿路结石形成机制的贡献。IV. 兔肾内草酸钙结晶的实验研究
Urol Res. 1979 Sep;7(3):223-6. doi: 10.1007/BF00257209.
2
Potential role of fluctuations in the composition of renal tubular fluid through the nephron in the initiation of Randall's plugs and calcium oxalate crystalluria in a computer model of renal function.在肾脏功能计算机模型中，通过肾单位的肾小管液成分波动在兰德尔斑和草酸钙结晶尿形成起始过程中的潜在作用。
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Calcium oxalate crystal growth in human urinary stones.草酸钙晶体在人体尿路结石中的生长
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Submicroscopic investigations on calcium oxalate stone genesis.草酸钙结石形成的亚微观研究。
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Scanning Microsc. 1995 Mar;9(1):89-100; discussion 100-1.
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引用本文的文献

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Canine calcium oxalate urolithiasis: Frequency of Whewellite and Weddellite stones from 1979 to 2015.犬草酸钙尿石症：1979年至2015年水草酸钙结石和二水草酸钙结石的发生率
Can Vet J. 2018 Dec;59(12):1305-1310.
2
Crystallisation of calcium oxalate dihydrate in normal urine in presence of sodium copper chlorophyllin.在叶绿酸铜钠存在的情况下，正常尿液中草酸钙二水合物的结晶。
Urol Res. 1982;10(4):173-6. doi: 10.1007/BF00255940.
3
Scanning electron microscopic investigations on the morphology and phase conversions of uroliths.尿路结石形态及相转变的扫描电子显微镜研究

本文引用的文献

1
[Uremia in subacute and chronic calciumoxalate kidney of endogenic origin; calciumoxalate nephritis kidney shrinkage].[内源性亚急性和慢性草酸钙肾病中的尿毒症；草酸钙肾炎性肾萎缩]
Schweiz Med Wochenschr. 1952 Dec 6;82(49):1261-6.
2
[Pathogenesis of experimental oxamide concrements in the rabbit kidney. Histological, histochemical, transmission and scanning electron microscopic studies].[兔肾实验性草酰胺结石的发病机制。组织学、组织化学、透射和扫描电子显微镜研究]
Urologe A. 1973 Jan;12(1):32-40.
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Urolithiasis induced with DL-3,a-dimethyltyrosine methylester HCl. I. A scanning electron microscopic investigation.
Int Urol Nephrol. 1979;11(1):11-20. doi: 10.1007/BF02082806.
用盐酸 DL-3，α-二甲基酪氨酸甲酯诱导的尿石症。I. 扫描电子显微镜研究。
Exp Pathol (Jena). 1975;10(1-2):1-27. doi: 10.1016/s0014-4908(75)80002-0.
4
A contribution to the formation mechanism of calcium oxalate urinary calculi. I. Stabilising urinary constituents in the formation of weddellite.草酸钙尿路结石形成机制的研究贡献。I. 稳定草酸钙二水合物形成过程中的尿液成分。
Urol Res. 1976 Nov 10;4(3):125-8. doi: 10.1007/BF00257168.
5
Oxalosis. An unusual cause of myelophthisis in childhood.草酸中毒。儿童期骨髓痨的一种罕见病因。
Am J Clin Pathol. 1976 Dec;66(6):991-7. doi: 10.1093/ajcp/66.6.991.
6
Crystaloptical and spectroscopical findings with calcium oxalate crystals in the urine sediment: a contribution to the genesis of oxalate stones.尿液沉渣中草酸钙晶体的晶体光学和光谱学研究结果：对草酸盐结石成因的贡献
Eur Urol. 1976;2(2):92-7. doi: 10.1159/000471970.
7
Renal tubular dysfunction secondary to jejunoileal bypass.空肠回肠旁路术后继发的肾小管功能障碍
JAMA. 1976 Mar 22;235(12):1257-8.
8
[Animal-experiment studies on the effect of magnesium and vitamin B 6 on calcium-oxalate nephrolithiasis].镁和维生素B6对草酸钙肾结石病影响的动物实验研究
Z Urol Nephrol. 1977 Jun;70(6):419-27.
9
Scanning electron microscopic investigations on the morphology and phase conversions of uroliths.尿路结石形态及相转变的扫描电子显微镜研究
Int Urol Nephrol. 1979;11(1):11-20. doi: 10.1007/BF02082806.
10
A contribution to the formation mechanism of calcium oxalate urinary calculi. III. On the role of magnesium in the formation of oxalate calculi.草酸钙尿路结石形成机制的研究。III. 镁在草酸盐结石形成中的作用。
Urol Res. 1976;4(4):161-7. doi: 10.1007/BF00262349.