Wekesa J W, Copeland R S, Mwangi R W
Department of Zoology, University of Nairobi, Kenya.
Am J Trop Med Hyg. 1992 Oct;47(4):484-8. doi: 10.4269/ajtmh.1992.47.484.
Feeding behavior was compared between infected and uninfected field-collected groups of Anopheles gambiae sensu lato and An. funestus from western Kenya. A significantly greater percentage (81%) of Plasmodium falciparum-infected An. gambiae s.l. females probed on experimental hosts (hamsters) than did uninfected females (38%). Among those females that initiated probing, there was no effect of infection status on the ability to take a bloodmeal. Plasmodium falciparum-infected An. gambiae s.l. probed more often (mean = 4.0) and for a longer time (mean = 277 sec) than did their uninfected counterparts (mean = 2.4 probes and mean probing time = 214 sec). Results for the small number of An. funestus that fed followed the same trend. Among infected An. gambiae s.l. females, there was no effect of sporozoite density on either the number of probes made or the total probing time. Among uninfected females, there was no difference in feeding behavior between nulliparous and parous females. In laboratory experiments, female age had no effect on blood-feeding behavior. Our findings provide evidence that natural malaria infection modifies the feeding behavior of Anopheles females.
对来自肯尼亚西部的冈比亚按蚊复合组和嗜人按蚊的野外采集感染组和未感染组的取食行为进行了比较。感染恶性疟原虫的冈比亚按蚊复合组雌蚊在实验宿主（仓鼠）上进行探测的比例（81%）显著高于未感染雌蚊（38%）。在那些开始探测的雌蚊中，感染状态对取食能力没有影响。感染恶性疟原虫的冈比亚按蚊复合组雌蚊比未感染的雌蚊探测更频繁（平均 = 4.0次）且时间更长（平均 = 277秒）（未感染雌蚊平均探测2.4次，平均探测时间 = 214秒）。少量取食的嗜人按蚊的结果也遵循相同趋势。在感染的冈比亚按蚊复合组雌蚊中，子孢子密度对探测次数或总探测时间均无影响。在未感染的雌蚊中，未产卵雌蚊和已产卵雌蚊的取食行为没有差异。在实验室实验中，雌蚊年龄对吸血行为没有影响。我们的研究结果提供了证据，表明自然疟疾感染会改变按蚊雌蚊的取食行为。
