[Animal experimental studies on the question of chemical prevention of congenital clefts. II. Studies on mouse cleft palates due to cyclophosphamide].

Embryotoxic and teratogenic effects were produced by cyclophosphamide in mice of the AB/Jena-Halle strain. The simultaneous administration of Solcoseryl tended to modify these noxious effects, significantly reducing the incidence of cleft palates to one half.