金黄色葡萄球菌β-内酰胺酶阻遏物的序列分析以及与两株产β-内酰胺酶粪肠球菌分离株的杂交研究。
Sequence analysis of the beta-lactamase repressor from Staphylococcus aureus and hybridization studies with two beta-lactamase-producing isolates of Enterococcus faecalis.
作者信息
Smith M C, Murray B E
机构信息
Center for Infectious Diseases, University of Texas Medical School, Houston 77030.
出版信息
Antimicrob Agents Chemother. 1992 Oct;36(10):2265-9. doi: 10.1128/AAC.36.10.2265.
Abstract
The putative beta-lactamase (Bla) repressor gene, blaI, from the staphylococcal plasmid pI524 was isolated, and the DNA sequence was determined. The sequence of blaI was found to be identical to the blaI sequence from pI9789 (blaI blaZ seg-1), a plasmid related to pI524. A blaI probe from pI524 was hybridized with plasmid and genomic DNA from Bla+ Enterococcus faecalis isolates HH22 and PA. The Bla structural gene of HH22 has been previously shown to be of staphylococcal origin, but DNA homologous to the staphylococcal Bla repressor was not found, indicating that the constitutive production of beta-lactamase in these E. faecalis isolates may be the result of a missing repressor protein.
摘要
从葡萄球菌质粒pI524中分离出假定的β-内酰胺酶（Bla）阻遏基因blaI，并测定了其DNA序列。发现blaI的序列与来自pI9789（blaI blaZ seg-1）的blaI序列相同，pI9789是一种与pI524相关的质粒。来自pI524的blaI探针与Bla+粪肠球菌分离株HH22和PA的质粒及基因组DNA进行杂交。先前已表明HH22的Bla结构基因源自葡萄球菌，但未发现与葡萄球菌Bla阻遏物同源的DNA，这表明这些粪肠球菌分离株中β-内酰胺酶的组成型产生可能是由于阻遏蛋白缺失所致。
相似文献
1
Sequence analysis of the beta-lactamase repressor from Staphylococcus aureus and hybridization studies with two beta-lactamase-producing isolates of Enterococcus faecalis.金黄色葡萄球菌β-内酰胺酶阻遏物的序列分析以及与两株产β-内酰胺酶粪肠球菌分离株的杂交研究。
Antimicrob Agents Chemother. 1992 Oct;36(10):2265-9. doi: 10.1128/AAC.36.10.2265.
2
Genes involved in the regulation of beta-lactamase production in enterococci and staphylococci.参与肠球菌和葡萄球菌中β-内酰胺酶产生调控的基因。
Antimicrob Agents Chemother. 1993 Sep;37(9):1966-70. doi: 10.1128/AAC.37.9.1966.
3
Nucleotide sequence of the beta-lactamase gene from Enterococcus faecalis HH22 and its similarity to staphylococcal beta-lactamase genes.粪肠球菌HH22β-内酰胺酶基因的核苷酸序列及其与葡萄球菌β-内酰胺酶基因的相似性。
Antimicrob Agents Chemother. 1991 Sep;35(9):1736-40. doi: 10.1128/AAC.35.9.1736.
4
Detection of genes regulating beta-lactamase production in Enterococcus faecalis and Staphylococcus aureus.粪肠球菌和金黄色葡萄球菌中调控β-内酰胺酶产生的基因检测
Antimicrob Agents Chemother. 1996 Nov;40(11):2550-4. doi: 10.1128/AAC.40.11.2550.
5
Comparison of enterococcal and staphylococcal beta-lactamase-encoding fragments.
Antimicrob Agents Chemother. 1992 Feb;36(2):273-6. doi: 10.1128/AAC.36.2.273.
6
Comparison of the beta-lactamase gene cluster in clonally distinct strains of Enterococcus faecalis.粪肠球菌克隆不同菌株中β-内酰胺酶基因簇的比较。
Antimicrob Agents Chemother. 1996 May;40(5):1170-4. doi: 10.1128/AAC.40.5.1170.
7
Comparison of enterococcal and staphylococcal beta-lactamase plasmids.
J Infect Dis. 1990 Jan;161(1):54-8. doi: 10.1093/infdis/161.1.54.
8
Characterization of a chromosomal gene encoding type B beta-lactamase in phage group II isolates of Staphylococcus aureus.金黄色葡萄球菌噬菌体II群分离株中编码B型β-内酰胺酶的染色体基因的特性分析
Antimicrob Agents Chemother. 1998 Dec;42(12):3163-8. doi: 10.1128/AAC.42.12.3163.
9
Insertions of IS256-like element flanking the chromosomal beta-lactamase gene of Enterococcus faecalis CX19.粪肠球菌CX19染色体β-内酰胺酶基因侧翼的类IS256元件插入情况
Antimicrob Agents Chemother. 1994 Apr;38(4):693-701. doi: 10.1128/AAC.38.4.693.
10
Studies of the repressor (BlaI) of beta-lactamase synthesis in Staphylococcus aureus.金黄色葡萄球菌中β-内酰胺酶合成阻遏物（BlaI）的研究。
Mol Microbiol. 1997 Jun;24(5):1025-37. doi: 10.1046/j.1365-2958.1997.4051770.x.
引用本文的文献
1
Vancomycin Resistance in and .[具体研究对象]中的万古霉素耐药性 以及[具体研究对象]。
你提供的原文信息不完整，我只能按照要求进行这样的翻译。请补充完整原文以便我能给出更准确的译文。
Microorganisms. 2022 Dec 21;11(1):24. doi: 10.3390/microorganisms11010024.
2
Detection of genes regulating beta-lactamase production in Enterococcus faecalis and Staphylococcus aureus.粪肠球菌和金黄色葡萄球菌中调控β-内酰胺酶产生的基因检测
Antimicrob Agents Chemother. 1996 Nov;40(11):2550-4. doi: 10.1128/AAC.40.11.2550.
3
Comparison of the beta-lactamase gene cluster in clonally distinct strains of Enterococcus faecalis.粪肠球菌克隆不同菌株中β-内酰胺酶基因簇的比较。
Antimicrob Agents Chemother. 1996 May;40(5):1170-4. doi: 10.1128/AAC.40.5.1170.
4
Genes involved in the regulation of beta-lactamase production in enterococci and staphylococci.参与肠球菌和葡萄球菌中β-内酰胺酶产生调控的基因。
Antimicrob Agents Chemother. 1993 Sep;37(9):1966-70. doi: 10.1128/AAC.37.9.1966.
5
Beta-lactamase-producing enterococci.产β-内酰胺酶肠球菌
Antimicrob Agents Chemother. 1992 Nov;36(11):2355-9. doi: 10.1128/AAC.36.11.2355.
6
New nucleotide sequence data on the EMBL File Server.欧洲分子生物学实验室文件服务器上的新核苷酸序列数据。
Nucleic Acids Res. 1992 Dec 25;20(24):6749-67. doi: 10.1093/nar/20.24.6749.
本文引用的文献
1
ANALYSIS BY TRANSDUCTION OF MUTATIONS AFFECTING PENICILLINASE FORMATION IN STAPHYLOCOCCUS AUREUS.通过转导分析影响金黄色葡萄球菌青霉素酶形成的突变
J Gen Microbiol. 1963 Oct;33:121-36. doi: 10.1099/00221287-33-1-121.
2
Transferable beta-lactamase. A new mechanism for in vitro penicillin resistance in Streptococcus faecalis.可转移的β-内酰胺酶。粪肠球菌体外青霉素耐药的一种新机制。
J Clin Invest. 1983 Sep;72(3):1168-71. doi: 10.1172/JCI111042.
3
The genetics of Bacillus licheniformis penicillinase: a preliminary analysis from studies on mutation and inter-strain and intra-strain transformations.地衣芽孢杆菌青霉素酶的遗传学：基于突变、菌株间及菌株内转化研究的初步分析
J Gen Microbiol. 1965 Oct;41(1):7-21. doi: 10.1099/00221287-41-1-7.
4
Naturally occurring penicillinase plasmids in Staphylococcus aureus.金黄色葡萄球菌中天然存在的青霉素酶质粒。
J Bacteriol. 1969 Apr;98(1):215-21. doi: 10.1128/jb.98.1.215-221.1969.
5
The genetics of penicillinase production in Staphylococcus aureus strain PS80.金黄色葡萄球菌PS80菌株中青霉素酶产生的遗传学
J Gen Microbiol. 1969 Dec;59(3):289-301. doi: 10.1099/00221287-59-3-289.
6
Analysis by transformation of the penicillinase system in Bacillus licheniformis.地衣芽孢杆菌青霉素酶系统转化分析。
J Gen Microbiol. 1973 May;76(1):217-30. doi: 10.1099/00221287-76-1-217.
7
Regulation of the penicillinase genes of Bacillus licheniformis: interaction of the pen repressor with its operators.地衣芽孢杆菌青霉素酶基因的调控：青霉素阻遏物与其操纵基因的相互作用。
J Bacteriol. 1988 Jul;170(7):3206-12. doi: 10.1128/jb.170.7.3206-3212.1988.
8
beta-Lactamase production in experimental endocarditis due to aminoglycoside-resistant Streptococcus faecalis.耐氨基糖苷类粪肠球菌所致实验性心内膜炎中β-内酰胺酶的产生
J Infect Dis. 1987 Jun;155(6):1226-32. doi: 10.1093/infdis/155.6.1226.
9
Nucleotide sequence of the penicillinase repressor gene penI of Bacillus licheniformis and regulation of penP and penI by the repressor.地衣芽孢杆菌青霉素酶阻遏基因penI的核苷酸序列以及阻遏物对penP和penI的调控
J Bacteriol. 1986 Dec;168(3):1128-32. doi: 10.1128/jb.168.3.1128-1132.1986.
10
In vitro studies of plasmid-mediated penicillinase from Streptococcus faecalis suggest a staphylococcal origin.来自粪肠球菌的质粒介导青霉素酶的体外研究表明其起源于葡萄球菌。
J Clin Invest. 1986 Jan;77(1):289-93. doi: 10.1172/JCI112289.
Zotero 插件