Cooke R W
Mersey Regional Neonatal Intensive Care Unit, Liverpool Maternity Hospital.
Arch Dis Child. 1992 Oct;67(10 Spec No):1174-6. doi: 10.1136/adc.67.10_spec_no.1174.
Annual odds ratios, standardised for known confounding variables, were used to examine trends in major neonatal morbidities among 3220 preterm infants of less than 35 weeks' gestation admitted to a regional referral centre between 1980 and 1991. Despite improved survival, the risk of major cerebral haemorrhage, ventriculoperitoneal shunt insertion, and necrotising enterocolitis was unchanged. A recent reduction in risk of pneumothorax and persistence of the arterial duct was noted. An increased risk for chronic lung disease over time could be accounted for by increased survival, although a similar increase in risk for infection remained unexplained.
采用针对已知混杂变量进行标准化处理的年度比值比，对1980年至1991年间收入某区域转诊中心的3220名孕周小于35周的早产儿的主要新生儿疾病发病趋势进行了研究。尽管存活率有所提高，但重大脑出血、脑室腹腔分流术及坏死性小肠结肠炎的风险并未改变。近期发现气胸和动脉导管未闭的风险有所降低。慢性肺病风险随时间增加可归因于存活率提高，不过感染风险的类似增加仍无法解释。
