Schmidt B K, Vegh P, Andrew M, Johnston M
Department of Pediatrics and Pathology, McMaster University, Hamilton, Ontario, Canada.
Arch Dis Child. 1992 Oct;67(10 Spec No):1196-7. doi: 10.1136/adc.67.10_spec_no.1196.
Forty seven infants in a prospective cohort of 170 high risk neonates without signs of overt bleeding had abnormal coagulation screening tests within 36 hours of birth. Early thrombocytopenia was a better predictor of prolonged prothrombin times and hypofibrinogenemia than very low birth weight, fetal growth retardation, or poor five minute Apgar scores.