Kojima T, Tanaka T, Yoshimi N, Mori H
First Department of Pathology, Gifu University School of Medicine, Japan.
Arch Pathol Lab Med. 1992 Nov;116(11):1213-6.
Primary malignant melanoma is an unusual neoplasm in the urinary bladder that is infrequently found in association with melanosis. We report a case of bladder-invasive malignant melanoma with melanosis in which the melanosis exhibited melanocytic atypia extending through to melanoma in situ and was diagnosed by immunohistochemical techniques using a monoclonal antibody, HMB-45. To our knowledge, such findings have not been reported previously.
原发性恶性黑色素瘤是膀胱中一种罕见的肿瘤，很少与黑变病相关联。我们报告一例伴有黑变病的膀胱浸润性恶性黑色素瘤病例，其中黑变病表现出黑素细胞异型性，延伸至原位黑色素瘤，并通过使用单克隆抗体HMB-45的免疫组织化学技术进行诊断。据我们所知，此前尚未有此类发现的报道。
