Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Department of Urology, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, Sichuan, People's Republic of China.
World J Surg Oncol. 2022 Sep 7;20(1):287. doi: 10.1186/s12957-022-02753-5.
Primary melanoma of the bladder is extremely rare and has been sporadically reported in case reports. Its incidence, diagnosis, treatment, and outcomes are still unclear.
We report a 67-year-old female patient who presented with hematuria and was diagnosed with primary melanoma of the bladder by transurethral resection. No distant metastasis was detected by fluorodeoxyglucose positron emission tomography-computed tomography (PET-CT). After a multidisciplinary discussion, the patient received laparoscopic radical resection of the bladder tumor. There was no tumor recurrence or distant metastasis after 15 months of follow-up.
Primary melanoma of the bladder is easily confused with urothelium carcinoma in morphology. The immunohistochemical is crucial in diagnosis. Because of a lack of in-depth understanding of primary melanoma of the bladder, the "gold standard" treatment has not been set. We would like to provide some rare information about it and discuss the proper treatment strategy for this rare disease.
膀胱原发性黑色素瘤极为罕见，仅有零星病例报告。其发病情况、诊断、治疗和预后尚不清楚。
我们报告了 1 例 67 岁女性患者，因血尿就诊，经尿道膀胱肿瘤电切术诊断为膀胱原发性黑色素瘤。氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描（PET-CT）未发现远处转移。经过多学科讨论，患者接受了腹腔镜根治性膀胱肿瘤切除术。术后 15 个月随访无肿瘤复发或远处转移。
膀胱原发性黑色素瘤在形态上容易与尿路上皮癌混淆。免疫组织化学在诊断中至关重要。由于对膀胱原发性黑色素瘤缺乏深入了解，尚未确立“金标准”治疗方法。我们希望提供一些有关该病的罕见信息，并讨论该罕见疾病的适当治疗策略。
