Stapleton F, Dart J, Minassian D
Moorfields Eye Hospital, London, England.
Arch Ophthalmol. 1992 Nov;110(11):1601-6. doi: 10.1001/archopht.1992.01080230101031.
A case-control study was used to evaluate the relative risk (RR) of acute contact lens-related disorders. The study sample comprised new patients wearing contact lens presenting at the accident and emergency department at Moorfields Eye Hospital, London, England, in 12 months. Disorders were classified by pathogenesis. Compared with gas-permeable hard contact lenses (the referent), extended-wear soft contact lenses were related to the largest overall RR for any complication (2.7 [95% confidence limits, 1.73, 4.16]), whereas for daily wear soft contact lenses the overall RR was 1.3 (confidence limits, 1.0, 1.72). Relative risks were greatest for extended-wear soft contact lens wearers with metabolic disorders (2.1 [confidence limits, 1.28, 3.4]) and for such wearers with sterile infiltrates (2.4 [confidence limits, 1.22, 4.84]). Among those using daily wear contact lenses, RR was highest for those with toxic/hypersensitivity disorders (5.9 [95% confidence limits, 3.27, 10.49]). Severe complications involving greater morbidity occurred more frequently with extended-wear soft contact lenses. This could be reduced by selecting a more appropriate lens type to correct low refractive errors.
一项病例对照研究用于评估急性隐形眼镜相关疾病的相对风险（RR）。研究样本包括在12个月内于英国伦敦穆尔菲尔德眼科医院急诊部就诊的佩戴隐形眼镜的新患者。疾病按发病机制分类。与透气硬性隐形眼镜（参照组）相比，长戴型软性隐形眼镜出现任何并发症的总体RR最高（2.7[95%置信区间，1.73，4.16]），而日戴型软性隐形眼镜的总体RR为1.3（置信区间，1.0，1.72）。长戴型软性隐形眼镜佩戴者出现代谢性疾病的相对风险最大（2.1[置信区间，1.28，3.4]），出现无菌浸润的相对风险也最大（2.4[置信区间，1.22，4.84]）。在日戴型隐形眼镜使用者中，有毒/过敏疾病患者的RR最高（5.9[95%置信区间，3.27，10.49]）。长戴型软性隐形眼镜更常出现涉及更高发病率的严重并发症。通过选择更合适的镜片类型来矫正低度屈光不正，这种情况可能会减少。
