Smiddy W E, Hernandez E
Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami (Fla) School of Medicine 33101.
Arch Ophthalmol. 1992 Nov;110(11):1630-3. doi: 10.1001/archopht.1992.01080230130037.
A retinal break and localized retinal detachment were induced in 10 rabbit eyes. The retinal break was treated within regions of detached retina using diode laser transscleral retinopexy (four eyes), diode laser indirect ophthalmoscopy (two eyes), or retinocryopexy (two eyes). Two eyes were left as untreated controls. The clinical and histopathologic effects were studied 1 day and 3 weeks after initial treatment. Suitable chorioretinal adhesions were induced with all treatment modalities. The extent of tissue effects was greater in cryopexy and smaller in laser treatment. The histopathologic characteristics of the lesions induced by diode laser indirect ophthalmoscopy were similar to those seen with transscleral diode treatment and were more focal than those seen with cryopexy. Transscleral and transpupillary diode laser photocoagulation were effective in inducing chorioretinal adhesions in detached retina in this experimental model in rabbits.
在10只兔眼中造成视网膜裂孔和局限性视网膜脱离。对脱离视网膜区域内的视网膜裂孔采用二极管激光经巩膜视网膜固定术（4只眼）、二极管激光间接检眼镜检查法（2只眼）或视网膜冷冻疗法（2只眼）进行治疗。2只眼留作未治疗对照。在初始治疗后1天和3周研究临床和组织病理学效应。所有治疗方式均诱导出了合适的脉络膜视网膜粘连。冷冻疗法的组织效应范围更大，激光治疗的组织效应范围更小。二极管激光间接检眼镜检查法所致病变的组织病理学特征与经巩膜二极管治疗所见相似，且比冷冻疗法所见更具局限性。在该兔实验模型中，经巩膜和经瞳孔二极管激光光凝术可有效诱导脱离视网膜中的脉络膜视网膜粘连。
