Grebski E, Hess T, Hold G, Speich R, Russi E
Department of Internal Medicine, University Hospital, Zurich, Switzerland.
Chest. 1992 Dec;102(6):1794-9. doi: 10.1378/chest.102.6.1794.
Our objective was to determine if the hemosiderin content of BAL macrophages allows us to draw any differential diagnostic conclusions in a variety of lung diseases.
One hundred one patients who underwent BAL for different diagnostic reasons were studied prospectively.
The highest values for the hemosiderin score (HS) were found in patients with active alveolar hemorrhage and patients who had undergone heart transplantation for congestive heart failure. Compared to a control population, patients with Pneumocystis carinii pneumonia or invasive aspergillosis had a higher HS than patients with bacterial pneumonia or mycobacterial lung infection. High or intermediate values for HS were more often found in patients with a low than in those with a normal platelet count.
The differential diagnostic conclusions which can be based on an HS are limited.
我们的目的是确定支气管肺泡灌洗（BAL）巨噬细胞中的含铁血黄素含量是否能让我们对多种肺部疾病得出任何鉴别诊断结论。
前瞻性地研究了101例因不同诊断原因接受BAL的患者。
在活动性肺泡出血患者和因充血性心力衰竭接受心脏移植的患者中发现含铁血黄素评分（HS）最高。与对照组相比，卡氏肺孢子虫肺炎或侵袭性曲霉病患者的HS高于细菌性肺炎或分枝杆菌肺部感染患者。血小板计数低的患者比血小板计数正常的患者更常出现高或中等HS值。
基于HS得出的鉴别诊断结论有限。
