Coskey R J, Mehregan A
Int J Dermatol. 1977 Nov;16(9):741-4. doi: 10.1111/j.1365-4362.1977.tb01893.x.
Most patients previously reported to have papular mucinosis had the generalized lichenoid papular form (scleromyxedema) with abnormal gamma globulin. Microscopic examination of affected skin showed increased acid mucopolysaccharides in the dermis and proliferation of fibroblasts. Our patient had the discrete form of papular mucinosis without abnormal serum gamma globulin but with increased amounts of acid mucopolysaccharides in the dermis and no proliferation of fibroblasts.
先前报道的大多数丘疹性粘蛋白病患者患有伴有异常γ球蛋白的泛发性苔藓样丘疹型(硬化性黏液水肿)。对受累皮肤进行显微镜检查发现真皮中酸性粘多糖增加和成纤维细胞增殖。我们的患者患有丘疹性粘蛋白病的离散型,血清γ球蛋白无异常,但真皮中酸性粘多糖含量增加且成纤维细胞无增殖。