Ahlström H, Lundström N R, Mortensson W, Ostberg G, Lantorp K
Acta Paediatr Scand. 1977 Mar;66(2):193-8. doi: 10.1111/j.1651-2227.1977.tb07832.x.
Coronary artery aneurysm in childhood is a rare disease and has in most cases been ascribed to infantile periarteritis nodosa (IPN). In recent years a mucocutaneous lymph node syndrom (MLNS) has been found almost exclusively in Japan first described by Kawasaki 1967; this disease frequently involves the coronary arteries and myocardium. Four cases with coronary aneurysms are presented from Sweden and seem to be first described from Scandinavia. Three of these patients died a sudden death with cardiac arrest. Since MLNS and IPN have identical clinical and pathological features, we suggest that MLNS and IPN constitute a pathologic entity and that to separate them on a clinical or histological basis is nonsensical. The risk of coronary aneurysm and possible sudden death must be considered in patients with uncharacteristic symptoms including prolonged fever, conjunctivitis, exanthema, lesions in the oral mucosa, elevated sedimintation rate, and leukocytosis.
儿童冠状动脉瘤是一种罕见疾病，在大多数情况下被归因于婴儿结节性动脉周围炎（IPN）。近年来，一种皮肤黏膜淋巴结综合征（MLNS）几乎仅在日本被发现，最初由川崎于1967年描述；这种疾病常累及冠状动脉和心肌。本文报告了来自瑞典的4例冠状动脉瘤病例，似乎是斯堪的纳维亚地区首次描述。其中3例患者因心脏骤停突然死亡。由于MLNS和IPN具有相同的临床和病理特征，我们认为MLNS和IPN构成一个病理实体，基于临床或组织学基础将它们区分开来是没有意义的。对于有非特异性症状（包括持续发热、结膜炎、皮疹、口腔黏膜病变、血沉升高和白细胞增多）的患者，必须考虑冠状动脉瘤和可能猝死的风险。
