早产儿对乙型肝炎疫苗的反应。

Response of preterm infants to hepatitis B vaccine.

作者信息

Lau Y L, Tam A Y, Ng K W, Tsoi N S, Lam B, Lam P, Yeung C Y

机构信息

Department of Pediatrics, University of Hong Kong, Queen Mary Hospital.

出版信息

J Pediatr. 1992 Dec;121(6):962-5. doi: 10.1016/s0022-3476(05)80352-x.

DOI:10.1016/s0022-3476(05)80352-x

PMID:1447667

Abstract

Ninety-nine preterm infants with birth weights < 1750 gm had three doses of hepatitis B vaccine. Fifty-seven received the first dose when they weighed > or = 1000 gm (group 1) and 42 when they weighed > or = 2000 gm (group 2). The final seropositive rates and geometric mean titers of group 1 infants (79%, 61 mIU/ml) and group 2 infants (91%, 262 mIU/ml) were less than that of 43 normal term infants (100%, 679 mIU/ml).

摘要

99名出生体重小于1750克的早产儿接种了三剂乙肝疫苗。57名婴儿在体重≥1000克时接种了第一剂（第1组），42名婴儿在体重≥2000克时接种了第一剂（第2组）。第1组婴儿（79%，61 mIU/ml）和第2组婴儿（91%，262 mIU/ml）的最终血清阳性率和几何平均滴度低于43名正常足月儿（100%，679 mIU/ml）。