甲状腺球蛋白抗体检测方法的比较
A comparison of tests for thyroglobulin antibody.
作者信息
RAWSTRON J R, FARTHING C P
出版信息
J Clin Pathol. 1962 Mar;15(2):153-5. doi: 10.1136/jcp.15.2.153.
A comparison is made of tests for thyroglobulin antibody, using gel diffusion, electroprecipitin, bentonite flocculation, tanned red cell agglutination, and latex slide agglutination techniques on sera from cases of Hashimoto's disease and other thyroid disorders. Any increase in gamma globulin was also noted from the serum electrophoretic pattern. The gel diffusion and electroprecipitin tests are shown to be comparable in their sensitivity, as are the bentonite flocculation and tanned red cell agglutination tests. The flocculation and agglutination tests were oversensitive. The latex slide test in conjunction with the electro-precipitin test is recommended for routine use in the detection of Hashimoto's disease.
对桥本氏病及其他甲状腺疾病患者血清，采用凝胶扩散、电沉淀、膨润土絮凝、鞣酸红细胞凝集和乳胶玻片凝集技术进行甲状腺球蛋白抗体检测，并进行比较。同时从血清电泳图谱中观察到γ球蛋白的任何增加。结果表明，凝胶扩散试验和电沉淀试验在敏感性方面相当，膨润土絮凝试验和鞣酸红细胞凝集试验也是如此。絮凝和凝集试验过于敏感。建议将乳胶玻片试验与电沉淀试验结合用于桥本氏病检测的常规应用。
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