Guy J M, Lamaud M, Da Costa A, Bouvet L, Cerisier A, Verneyre H
Service de cardiologie, hôpital Nord, Saint-Priest-en-Jarez.
Arch Mal Coeur Vaiss. 1992 Jul;85(7):1047-9.
A 42 year old woman presented with a one year history of retrosternal chest pain and back pain on effort and at rest sometimes accompanied by minor syncopal attacks. Transient atrioventricular block was documented during one such episode associated with hypotension. Coronary angiography showed spontaneous spasm of the left main coronary artery with clinical symptoms but no electrocardiographic changes. The spasm was relieved by injection of SIN-1. The similarity between the previous clinical symptoms and those observed at coronary angiography was in favour of the diagnosis of spasm of the left main coronary artery without atherosclerotic coronary disease. Treatment with calcium atherosclerotic coronary disease. Treatment with calcium blockers and platelet antiaggregants led to total regression of her symptoms with a follow-up of 5 months.
一名42岁女性,有一年的病史,表现为胸骨后胸痛和用力及休息时的背痛,有时伴有轻微晕厥发作。在一次与低血压相关的此类发作期间记录到短暂性房室传导阻滞。冠状动脉造影显示左主干冠状动脉自发痉挛,伴有临床症状但无心电图改变。注射SIN-1后痉挛缓解。先前临床症状与冠状动脉造影时观察到的症状相似,支持无动脉粥样硬化性冠状动脉疾病的左主干冠状动脉痉挛的诊断。使用钙通道阻滞剂和血小板抗聚集剂治疗,随访5个月,其症状完全缓解。