DeFoor Willam, Minevich Eugene, Reeves Deborah, Tackett Leslie, Wacksman Jeffrey, Sheldon Curtis
Division of Pediatric Urology, Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA.
J Urol. 2003 Oct;170(4 Pt 2):1647-9; discussion 1649-50. doi: 10.1097/01.ju.0000091220.86291.96.
The use of stomach has become controversial in pediatric lower urinary tract reconstruction. Recent series have reported a high incidence of hematuria-dysuria syndrome and metabolic abnormalities, which has prompted a significant decrease in its use at our institution during the last 5 years.
We retrospectively reviewed the medical records of children who underwent urinary reconstruction with gastrocystoplasty. Patients were excluded from consideration if they had less than 5 years of followup.
From 1989 to 1997, 18 males and 26 females were identified. Median patient age at time of reconstruction was 4.5 years and median followup was 9.8 years. Urinary continence was present in 89% of cases, and upper tract dilatation was stable or improved in 91%. No patient had chronic metabolic alkalosis. Major surgery was required for complications of the gastrocystoplasty in 6 cases, including patch contraction and ureteral obstruction necessitating excision in 1. Two patients had severe hematuria while anuric from renal failure which was managed conservatively with bladder cycling and H2 blockers. Symptoms resolved completely after renal transplantation in both cases. Febrile urinary tract infection occurred in 20% of cases and asymptomatic bacteriuria was present in 36%.
The use of stomach segments in pediatric urinary reconstruction can be beneficial in patients with chronic renal insufficiency, metabolic acidosis or short gut syndrome. Despite negative reports concerning serious complications of gastrocystoplasty, our long-term data confirm that it remains an important option in our reconstruction armamentarium.
在小儿下尿路重建中,胃的应用已引发争议。近期系列报道显示血尿-排尿困难综合征及代谢异常的发生率很高,这促使我院在过去5年中显著减少了胃的使用。
我们回顾性分析了接受胃膀胱扩大术进行尿路重建的儿童的病历。随访时间不足5年的患者被排除在研究之外。
1989年至1997年,共确定了18例男性和26例女性患者。重建时的中位患者年龄为4.5岁,中位随访时间为9.8年。89%的病例实现了尿失禁,91%的病例上尿路扩张稳定或有所改善。无患者出现慢性代谢性碱中毒。6例患者因胃膀胱扩大术的并发症需要进行大手术,其中1例因补片挛缩和输尿管梗阻需要切除。2例患者在肾衰竭无尿时出现严重血尿,通过膀胱循环和H2受体阻滞剂进行保守治疗。两例患者在肾移植后症状完全缓解。20%的病例发生发热性尿路感染,36%的病例存在无症状菌尿。
对于慢性肾功能不全、代谢性酸中毒或短肠综合征患者,小儿尿路重建中使用胃段可能有益。尽管有关于胃膀胱扩大术严重并发症的负面报道,但我们的长期数据证实,它仍然是我们重建手段中的一个重要选择。