Chong Ng Leslie, Sell Phillip
Department of Orthopaedic Surgery, Leicester General Hospital, Leicester, England.
Spine (Phila Pa 1976). 2003 Sep 15;28(18):E355-8. doi: 10.1097/01.BRS.0000084557.38858.85.
A case report and literature review of Gorham disease involving the cervical spine.
To describe the clinical course and surgical management of Gorham disease of the cervical spine. The pathologic features and various treatment methods are also discussed.
Gorham disease is a rare idiopathic disease that possesses distinctive clinical, pathologic, and radiologic features. It is a variant form of osseous angiomatosis associated with massive osteolysis of bone. Eight cases with cervical involvement have been reviewed in the literature and five cases were fatal.
We reported a 49-year-old man with Gorham disease of the cervical spine. Repeated surgical attempts to stabilize the cervical spine were required due to progression of the disease.
The patient has achieved a satisfactory functional outcome and remains fully independent.
In summary, Gorham disease is a rare entity with an unclear etiology. The long indolent course with the presence of radiographic and pathologic findings usually provides the diagnosis. There is no consensus on treatment, and evaluation of the treatment options is difficult due to the unknown natural history.
一项关于累及颈椎的戈勒姆病的病例报告及文献综述。
描述颈椎戈勒姆病的临床病程及手术治疗情况。同时讨论其病理特征及各种治疗方法。
戈勒姆病是一种罕见的特发性疾病，具有独特的临床、病理和放射学特征。它是骨血管瘤病的一种变异形式，伴有骨的大量骨质溶解。文献中已回顾了8例累及颈椎的病例，其中5例死亡。
我们报告了一名49岁患有颈椎戈勒姆病的男性患者。由于病情进展，需要反复进行手术以稳定颈椎。
患者获得了满意的功能结果，仍完全独立生活。
总之，戈勒姆病是一种病因不明的罕见疾病。其漫长的隐匿病程以及影像学和病理学表现通常可作出诊断。对于治疗尚无共识，且由于其自然病史未知，难以评估治疗方案。
