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强直性脊柱炎患者创伤性颈椎骨折的手术疗效

Surgical outcomes of traumatic cervical fractures in patients with ankylosing spondylitis.

作者信息

Isla Guerrero Alberto, Mansilla Fernández Beatriz, Hernández Garcia Borja, Gómez de la Riva Álvaro, Gandía González María Luisa, Isla Paredes Elena

机构信息

Sección de Neurocirugía, Hospital Universitario La Paz, Madrid, España.

Sección de Neurocirugía, Hospital Universitario La Paz, Madrid, España.

出版信息

Neurocirugia (Astur : Engl Ed). 2018 May-Jun;29(3):116-121. doi: 10.1016/j.neucir.2017.11.001. Epub 2018 Jan 12.

Abstract

OBJECTIVE

Ankylosing spondylitis is an inflammatory rheumatic disease mainly affecting the axial skeleton. The rigid spine may secondarily develop osteoporosis, further increasing the risk of spinal fracture. In this study, we reviewed fractures in patients with ankylosing spondylitis that had been clinically diagnosed to better define the mechanism of injury, associated neurological deficit, predisposing factors, and management strategies.

METHODS

Between January 2004 and December 2014, 6 patients with ankylosing spondylitis and neurological complications after injuries were treated. Neuroimaging evaluation was obtained in all patients by using plain radiography, CT scan, and MR imaging. The ASIA Impairment Scale was used in order to evaluate the neurologic status of the patients. Surgical decision was based on relationship of neurological involvement and spinal instability.

RESULTS

A total of 6 cervical injuries were identified in a review of patients in whom ankylosing spondylitis had been diagnosed. Of these, 2 patients were associated with a hyperextension mechanism and 4 cases by flexion mechanism. Posttraumatic neurological deficits were demonstrated in all 6 cases and neurological improvement after surgery was observed in 4 of these cases. The two cases were not improved by the surgery was on a case by presenting a degree of Asia A and another patient who initially improved with surgery but died of pneumonia in the postoperative.

CONCLUSIONS

Patients with ankylosing spondylitis are highly susceptible to spinal fracture and spinal cord injury even after only mild trauma. Initial CT or MR imaging of the whole spine is recommended even if the patient's symptoms are mild. The patient should also have early surgical stabilization to correct spinal deformity and avoid worsening of the patient's neurological status.

摘要

目的

强直性脊柱炎是一种主要影响中轴骨骼的炎性风湿性疾病。僵硬的脊柱可能继发骨质疏松,进一步增加脊柱骨折的风险。在本研究中,我们回顾了临床诊断为强直性脊柱炎患者的骨折情况,以更好地明确损伤机制、相关神经功能缺损、易感因素及治疗策略。

方法

2004年1月至2014年12月,对6例强直性脊柱炎合并损伤后神经并发症的患者进行了治疗。所有患者均通过X线平片、CT扫描和磁共振成像进行神经影像学评估。采用美国脊髓损伤协会(ASIA)损伤分级量表评估患者的神经状态。手术决策基于神经受累情况与脊柱稳定性的关系。

结果

在回顾诊断为强直性脊柱炎的患者时,共发现6例颈椎损伤。其中,2例与过伸机制有关,4例与屈曲机制有关。所有6例均出现创伤后神经功能缺损,其中4例术后神经功能有改善。2例手术效果不佳,1例为ASIA A级,另1例术后最初有所改善,但死于肺炎。

结论

强直性脊柱炎患者即使仅受到轻度创伤,也极易发生脊柱骨折和脊髓损伤。即使患者症状轻微,也建议早期进行全脊柱CT或磁共振成像检查。患者还应尽早进行手术固定,以纠正脊柱畸形,避免神经状态恶化。

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