Jenkins R, Harrison H, Chen B, Arnold D, Funk J
Department of Pediatrics, University of Louisville, KY 40292.
ASAIO J. 1992 Oct-Dec;38(4):808-10.
Most extracorporeal continuous renal replacement therapies (CRRT) require inflow pumping of either dialysate, filtrate replacement solution, or both. Outflow of spent dialysate and ultrafiltrate can be accomplished by gravity drainage or pump. Intravenous infusion pumps have been commonly used for these purposes, although little is known about the accuracy of these pumps. To evaluate accuracy of two different types of intravenous infusion pumps used in CRRT, we studied flow rates at nine different pressure variations in three piston type and three linear peristaltic pumps. The results showed that error of either pump was not different for flow rates of 4 and 16 ml/min. Both types of pumps were affected by fluid circuit pressures, although pressure conditions under which error was low were different for each pump type. The linear peristaltic pumps were most accurate under conditions of low pump inlet pressure, whereas piston pumps were most accurate under conditions of low pump pressure gradient (outlet minus inlet) of 0 or -100 mmHg. The magnitude of error outside these conditions was substantial, reaching 12.5% for the linear peristaltic pump when inlet pressure was -100 mmHg and outlet pressure was 100 mmHg. Error may be minimized in the clinical setting by choosing the pump type best suited for the pressure conditions expected for the renal replacement modality in use.
大多数体外连续性肾脏替代疗法（CRRT）需要对透析液、置换液或两者进行流入泵注。用过的透析液和超滤液的流出可通过重力引流或泵来实现。静脉输液泵通常用于这些目的，尽管对这些泵的准确性了解甚少。为了评估CRRT中使用的两种不同类型静脉输液泵的准确性，我们研究了三种活塞式泵和三种线性蠕动泵在九种不同压力变化下的流速。结果表明，对于4和16毫升/分钟的流速，两种泵的误差没有差异。两种类型的泵都受液体回路压力的影响，尽管每种泵误差较低时的压力条件不同。线性蠕动泵在泵入口压力较低的条件下最准确，而活塞泵在泵压力梯度（出口减去入口）为0或-100毫米汞柱的低压力条件下最准确。在这些条件之外，误差幅度很大，当入口压力为-100毫米汞柱且出口压力为100毫米汞柱时，线性蠕动泵的误差达到12.5%。在临床环境中，通过选择最适合所用肾脏替代方式预期压力条件的泵类型，误差可能会降至最低。
