Polesky Andrea, Bhatia Gulshan
Santa Clara County Tuberculosis Clinic, Santa Clara Valley Health and Hospital System, San Jose, CA, USA.
Semin Respir Infect. 2003 Sep;18(3):206-15.
Viral hemorrhagic fevers are among a small group of infectious diseases considered potential candidates for use as agents of bioterrorism. Ebola hemorrhagic fever, the focus of this article, has the highest mortality rate of the viral hemorrhagic fevers and has no effective treatment. It is transmitted easily to family members and health care professionals not following universal precautions. The history of this infection, its clinical presentation, and epidemiology are discussed. Attention is paid to the immunopathogenesis of the disease with a focus on pulmonary involvement. Recommendations for infection control and Ebola virus' potential as a bioterrorism agent are addressed.
病毒性出血热是一小类被认为有可能用作生物恐怖主义制剂的传染病。本文重点关注的埃博拉出血热，在病毒性出血热中死亡率最高，且没有有效的治疗方法。它很容易传播给未采取普遍预防措施的家庭成员和医护人员。本文讨论了这种感染的历史、临床表现及流行病学。文中关注了该疾病的免疫发病机制，重点是肺部受累情况。还阐述了感染控制的建议以及埃博拉病毒作为生物恐怖主义制剂的潜在威胁。
