去唾液酸低密度脂蛋白与动脉粥样硬化
Desialylated low density lipoproteins and atherosclerosis.
作者信息
Dousset N, Dousset J C, Soléra M L, Valdiguié P
机构信息
Department of Biochemistry, Rangueil University Hospital, Toulouse, France.
出版信息
EXS. 1992;62:158-63. doi: 10.1007/978-3-0348-7460-1_16.
Oxidative modification of LDL is accompanied by a number of compositional and structural changes, now well known. In addition, other atherogenic modifications of LDL exist, such as desialylation. The present article summarizes the recent data related to desialylated LDL and to the presence of these LDL in blood plasma of patients with coronary atherosclerosis. In addition, this review examines the sensitivity of these LDL to peroxidative stress.
低密度脂蛋白（LDL）的氧化修饰伴随着许多已为人熟知的成分和结构变化。此外，还存在其他致动脉粥样硬化的LDL修饰，如去唾液酸化。本文总结了与去唾液酸化LDL以及这些LDL在冠状动脉粥样硬化患者血浆中的存在情况相关的最新数据。此外，本综述还研究了这些LDL对过氧化应激的敏感性。
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