软骨素O-甲酯：软骨素AC裂解酶的一种特殊底物。

Chondroitin O-methyl ester: an unusual substrate for chondroitin AC lyase.

作者信息

Avci Fikri Y, Toida Toshihiko, Linhardt Robert J

机构信息

Department of Chemistry, Rensselaer Polytechnic Institute,Troy, NY 12180-3590, USA.

出版信息

Carbohydr Res. 2003 Sep 26;338(20):2101-4. doi: 10.1016/s0008-6215(03)00348-3.

DOI:10.1016/s0008-6215(03)00348-3

PMID:14505877

Abstract

Chondroitin O-methyl ester was depolymerized by chondroitin AC lyase (EC 4.2.2.5) from Flavobacterium heparinum. The major product isolated from the depolymerization reaction was found to be methyl alpha-L-threo-hex-4-enopyranosyluronate-(1-->4)-2-acetamido-2-deoxy-alpha,beta-D-galactopyranoside.

摘要

硫酸软骨素 O-甲酯被来自肝素黄杆菌的硫酸软骨素 AC 裂合酶（EC 4.2.2.5）解聚。从解聚反应中分离出的主要产物被发现是α-L-苏式-己-4-烯吡喃糖醛酸-(1→4)-2-乙酰氨基-2-脱氧-α,β-D-吡喃半乳糖苷。