Giacchino R, Nocera A, Timitilli A, Cristina E, Giambartolomei G, Caocci F, Cirillo C, Barocci S
I Clinica Malattie Infettive, Università di Genova, Italy.
Arch Virol Suppl. 1992;4:281-3. doi: 10.1007/978-3-7091-5633-9_63.
In this preliminary study, children with chronic HBV hepatitis, as was also previously shown for adults, respond to interferon therapy in an HLA class I antigen dependent manner. If this can be confirmed on a large scale, HLA typing may serve as a useful indication of interferon-therapy responders.
在这项初步研究中,慢性乙型肝炎病毒肝炎患儿与成人一样,对干扰素治疗的反应具有HLA I类抗原依赖性。如果这一点能在大规模研究中得到证实,HLA分型可能会成为干扰素治疗反应者的有用指标。