Terry Mark A, Ousley Paula J
Devers Eye Institute, Portland, Oregon 97210, USA.
Cornea. 2003 Oct;22(7):619-26. doi: 10.1097/00003226-200310000-00006.
To determine if the new technique for endothelial transplantation of DLEK (deep lamellar endothelial keratoplasty) can offer predictable corneal curvature and improved refractive spherical equivalent results compared with reports for traditional penetrating keratoplasty.
Twenty-seven consecutive Fuchs corneal dystrophy patients received DLEK surgery to replace their endothelium. Topographic corneal curvature and refractive spherical equivalents were evaluated at preop and at 6 and 12 months postop.
At 6 months (n = 27) the average corneal curvature was 43.8 +/- 1.4 D, representing a mean change from preop corneal curvature of only -0.1 +/- 1.7 D. At 12 months (n = 18) the average corneal power was 43.5 +/- 1.7 D. The average corneal curvature at 6 and 12 months was not significantly different from pre-op (P = 0.119). The average refractive spherical equivalent result at 6 months was -0.44 +/- 1.7 D, and at 12 months was -0.44 +/- 1.6 D. The 6- and 12-month refractive spherical equivalent results were not statistically different from the preop spherical equivalent refractions (P = 0.922). All patients could be easily refracted, and several patients were fit with stable glasses as early as 3 months after DLEK surgery.
DLEK surgery preserves the preoperative corneal curvature and therefore allows better matching of postop corneal curvature to the IOL power. This increase in predictability of the postoperative corneal curvature makes the choice of IOL power for the new "triple procedure" more accurate, eliminates the need for contact lens wear after PK, and provides earlier visual rehabilitation after endothelial replacement.
确定与传统穿透性角膜移植术的报告相比,深板层内皮角膜移植术(DLEK)的内皮移植新技术是否能提供可预测的角膜曲率并改善屈光球镜等效值结果。
27例连续性Fuchs角膜营养不良患者接受DLEK手术以置换其内皮。术前以及术后6个月和12个月评估角膜地形图曲率和屈光球镜等效值。
6个月时(n = 27),平均角膜曲率为43.8±1.4 D,相对于术前角膜曲率的平均变化仅为-0.1±1.7 D。12个月时(n = 18),平均角膜屈光力为43.5±1.7 D。6个月和12个月时的平均角膜曲率与术前无显著差异(P = 0.119)。6个月时的平均屈光球镜等效值结果为-0.44±1.7 D,12个月时为-0.44±1.6 D。6个月和12个月时的屈光球镜等效值结果与术前球镜等效值验光结果无统计学差异(P = 0.922)。所有患者均可轻松验光,并且有几位患者在DLEK手术后3个月就可佩戴稳定的眼镜。
DLEK手术保留了术前角膜曲率,因此能使术后角膜曲率与人工晶状体屈光度更好地匹配。术后角膜曲率可预测性的提高使得新型“三联手术”中人工晶状体屈光度的选择更加准确,消除了穿透性角膜移植术后佩戴隐形眼镜的需求,并在内皮置换后提供了更早的视力康复。