Waxmonsky James
State University of New York at Buffalo, Department of Psychiatry, USA.
Curr Opin Pediatr. 2003 Oct;15(5):476-82. doi: 10.1097/00008480-200310000-00006.
Attention deficit hyperactivity disorder (ADHD) frequently occurs with a wide variety of comorbid psychiatric disorders such as conduct disorder, depression, mania, anxiety, and learning disabilities. Because the vast majority of children with ADHD are treated in primary care settings, it is important that primary medical doctors be proficient in the diagnosis and initial treatment of children with ADHD and its commonly occurring comorbid disorders. ADHD research is beginning to focus on the treatment of these comorbidly ill children. This review will summarize the recent findings from the psychiatric literature in an attempt to provide the clinician with some initial diagnostic and treatment guidelines for ADHD and its comorbidities.
The NIMH Multimodal Treatment Study of ADHD found that children with other disruptive behavior disorders plus ADHD respond well to stimulant medications, with behavioral interventions reducing academic and social impairment. Children with anxiety and ADHD are very responsive across multiple dimensions to behavioral and pharmacological ADHD treatments. Much less is known about the impact of depression on ADHD, and significant debate exists surrounding the identification and treatment of bipolar disorder in children with ADHD. Children with learning disabilities respond well to stimulants but often require additional educational supports. New findings suggest that treating ADHD may prevent the development of future psychiatric disorders.
The presence of comorbid illness is associated with significant additional morbidity and complicates the diagnosis, treatment, and prognosis of ADHD. Therefore, it is important to identify and treat any comorbid psychiatric conditions in a child with ADHD.
注意缺陷多动障碍(ADHD)常与多种共病的精神障碍同时出现,如品行障碍、抑郁、躁狂、焦虑和学习障碍。由于绝大多数患有ADHD的儿童在初级保健机构接受治疗,因此初级医生精通ADHD儿童及其常见共病的诊断和初始治疗非常重要。ADHD研究开始关注这些患有共病的儿童的治疗。本综述将总结精神科文献中的最新发现,试图为临床医生提供一些关于ADHD及其共病的初步诊断和治疗指南。
美国国立精神卫生研究所(NIMH)的ADHD多模式治疗研究发现,患有其他破坏性行为障碍合并ADHD的儿童对兴奋剂药物反应良好,行为干预可减少学业和社交障碍。患有焦虑和ADHD的儿童在多个维度上对ADHD的行为和药物治疗反应都很灵敏。关于抑郁对ADHD的影响了解较少,并且围绕ADHD儿童双相情感障碍的识别和治疗存在重大争议。患有学习障碍的儿童对兴奋剂反应良好,但通常需要额外的教育支持。新的发现表明,治疗ADHD可能预防未来精神障碍的发生。
共病的存在与显著增加的发病率相关,并使ADHD的诊断、治疗和预后复杂化。因此,识别并治疗ADHD儿童的任何共病精神状况很重要。