Marson L, List M S, McKenna K E
Department of Physiology, Northwestern University Medical School, Chicago, IL 60611.
Brain Res. 1992 Oct 2;592(1-2):187-92. doi: 10.1016/0006-8993(92)91675-5.
The effects of electrolytic lesions of the rostral nucleus paragigantocellularis (nPGi) were examined on ex copula sexual reflexes in male rats. Bilateral lesions of the nPGi significantly reduced (by 50%) the onset of the first ex copula reflex, which usually was a glans erection. In addition, the number of dorsiflexions (flips) was significantly increased. In the anesthetized spinally intact rat the urethrogenital reflex cannot be evoked. However, after chronic bilateral lesions of the rostral nPGi, half of the rats tested displayed the urethrogenital reflex prior to section of the spinal cord. These data support a role for the rostral nPGi in the descending inhibition of male sexual reflexes.
研究了吻侧巨细胞旁核（nPGi）电解损伤对雄性大鼠交配后性反射的影响。nPGi的双侧损伤显著降低了（50%）首次交配后反射的起始，该反射通常为龟头勃起。此外，背屈（翻转）次数显著增加。在麻醉的脊髓完整大鼠中，无法诱发尿道生殖反射。然而，在吻侧nPGi慢性双侧损伤后，一半接受测试的大鼠在脊髓横断前表现出尿道生殖反射。这些数据支持吻侧nPGi在雄性性反射下行抑制中的作用。
