Dhar Sorabh, Kulaylat Mahmoud N, Gordon Kelly, Lall Purin, Doerr Ralph J
Department of Surgery, State University of New York at Buffalo, Buffalo, New York, USA.
Am Surg. 2003 Sep;69(9):799-803.
Breast carcinoma has the potential for widespread dissemination. Spread to the lower gastrointestinal tract is infrequent, often multifocal, occurs in association with spread to other sites, and most commonly develops from lobular carcinoma. Solitary colorectal metastasis as the first and sole manifestation of spread is a rare occurrence and can be confused with primary intestinal malignancy. We present a case of metastatic papillary breast carcinoma presenting as a perforated primary colon cancer. Identity of the lesion was confirmed by direct histologic comparison of the resected tumor with prior breast specimen, cytokeratin expression, and the presence of estrogen receptors.
乳腺癌有广泛播散的可能。其向胃肠道下段的转移并不常见，通常为多灶性，常与向其他部位的转移同时发生，最常见于小叶癌。孤立性结直肠转移作为转移的首发且唯一表现是一种罕见情况，可能会与原发性肠道恶性肿瘤相混淆。我们报告一例以原发性结肠癌穿孔形式出现的转移性乳头状乳腺癌病例。通过将切除的肿瘤与先前的乳腺标本进行直接组织学比较、细胞角蛋白表达以及雌激素受体的存在来确认病变的性质。
