Liu Min, Andrews Ross, Stylianopoulos Joanne, Ferreira Catherine, Hogg Geoff, Pyper Nyree
Public Heath Training Scheme, Department of Human Services, Victoria.
Commun Dis Intell Q Rep. 2003;27(3):362-6. doi: 10.33321/cdi.2003.27.61.
This study analysed notification data from the first year of enhanced surveillance of invasive pneumococcal disease (IPD) in Victoria (1 July 2001 - 30 June 2002), with a focus on risk factors for infection and vaccination status among children under five years of age. Overall, there were 397 notifications (8.2 per 100,000 population), 131 (33%) were children under five years of age. The highest notification rates were among those aged less than two years (72.6 per 100,000 population). Among children aged less than five years: bacteraemia without a primary focus of infection was the most common clinical presentation (64%); 89 per cent were hospitalised with the median length of stay being three days; four children (3%) died. There were 107 cases of a known serotype, 92% (n = 98) were either in or closely related to those included in the 7-valent conjugate pneumococcal vaccine (7vPCV). Most cases (98%) were not eligible for free 7vPCV under the currently funded program in Victoria. Only one child had been vaccinated. The results from the first year of enhanced IPD surveillance in Victoria suggest consideration should be given to extending the publicly funded program to include all children under two years of age.
本研究分析了维多利亚州加强侵袭性肺炎球菌疾病（IPD）监测第一年（2001年7月1日至2002年6月30日）的通报数据，重点关注五岁以下儿童的感染风险因素和疫苗接种状况。总体而言，共收到397份通报（每10万人中有8.2例），其中131例（33%）为五岁以下儿童。通报率最高的是两岁以下儿童（每10万人中有72.6例）。在五岁以下儿童中：无原发性感染灶的菌血症是最常见的临床表现（64%）；89%的患儿住院，中位住院时间为三天；四名儿童（3%）死亡。已知血清型的病例有107例，92%（n = 98）属于7价肺炎球菌结合疫苗（7vPCV）所涵盖或与之密切相关的血清型。根据维多利亚州目前资助的项目，大多数病例（98%）不符合免费接种7vPCV的条件。只有一名儿童接种过疫苗。维多利亚州加强IPD监测第一年的结果表明，应考虑将公共资助项目扩大到包括所有两岁以下儿童。
