Bressler C, Himes L C, Moreau R E
Beach Animal Hospital, 208 River Avenue, Point Pleasant Beach, New Jersey 08742, USA.
J Small Anim Pract. 2003 Sep;44(9):408-10. doi: 10.1111/j.1748-5827.2003.tb00177.x.
A six-year-old, neutered male Siberian husky was presented for euthanasia for end-stage liver disease. Examination of the dog raised questions regarding the severity of the condition. It had presented to the referring veterinarian with polyuria, polydipsia and weight loss. Blood tests at that time revealed elevated liver enzymes and hypoalbuminaemia. Cirrhosis was presumptively diagnosed, based on an ultrasound examination, which showed ascites with a normal liver. The dog had a history of hypothyroidism, which was controlled with levothyroxine. Physical examination revealed cachexia. A second abdominal ultrasound examination was performed and revealed portal vein and aortic thromboses. Tick titres showed a positive Ehrlichia canis titre of 1:640. Skin biopsies showed lymphoplasmacytic vasculitis. Doxycycline and aspirin treatment was initiated, and the clinical signs resolved. The authors concluded that the thrombi were primarily caused by chronic ehrlichiosis, based on the clinical findings and the response to treatment.
一只六岁的绝育雄性西伯利亚哈士奇因终末期肝病被送来实施安乐死。对这只狗的检查引发了对病情严重程度的疑问。它最初被转诊兽医诊断为多尿、多饮和体重减轻。当时的血液检查显示肝酶升高和低白蛋白血症。根据超声检查结果推测诊断为肝硬化，超声显示有腹水但肝脏正常。这只狗有甲状腺功能减退病史，一直用左甲状腺素控制。体格检查发现恶病质。进行了第二次腹部超声检查，发现门静脉和主动脉血栓形成。蜱虫滴度显示犬埃立克体滴度为1:640阳性。皮肤活检显示淋巴细胞浆细胞性血管炎。开始使用强力霉素和阿司匹林治疗，临床症状得到缓解。基于临床发现和对治疗的反应，作者得出结论，血栓主要是由慢性埃立克体病引起的。
