Sato Naoyuki, Yamaguchi Yoko
Laboratory for Dynamics of Emergent Intelligence, RIKEN BSI, and CREST, Japan Science and Technology Corporation, Hirosawa, Wako-shi, Saitama 351-0198, Japan.
Neural Comput. 2003 Oct;15(10):2379-97. doi: 10.1162/089976603322362400.
Recent experimental evidence on spike-timing-dependent plasticity and on phase precession (i.e., the theta rhythm dependent firing of rat hippocampal cells) associates the contribution of phase precession to episodic memory. This article aims at clarifying the role of phase precession in memory storage. Computer simulations show that the memory storage in the behavioral timescale varies in timescale of the temporal sequence from half a second to several seconds. In contrast, the memory storage caused by traditional rate coding is restricted to the temporal sequence within 40 ms. During phase precession, memory storage of a single trial experience is possible, even in the presence of noise. It is therefore concluded that encoding by phase precession is appropriate for memory storage of the temporal sequence in the behavioral timescale.
近期关于尖峰时间依赖性可塑性和相位进动（即大鼠海马体细胞的θ节律依赖性放电）的实验证据，将相位进动的作用与情景记忆联系起来。本文旨在阐明相位进动在记忆存储中的作用。计算机模拟表明，行为时间尺度上的记忆存储在时间序列的时间尺度上从半秒到几秒不等。相比之下，传统速率编码引起的记忆存储局限于40毫秒内的时间序列。在相位进动期间，即使存在噪声，单次试验经历的记忆存储也是可能的。因此得出结论，通过相位进动进行编码适用于行为时间尺度上时间序列的记忆存储。
