分裂型人格障碍中梭状回的磁共振成像研究。
A MRI study of fusiform gyrus in schizotypal personality disorder.
作者信息
Dickey Chandlee C, McCarley Robert W, Voglmaier Martina M, Niznikiewicz Margaret A, Seidman Larry J, Frumin Melissa, Toner Sarah, Demeo Susan, Shenton Martha E
机构信息
Laboratory of Neuroscience, Department of Psychiatry, VA Boston Healthcare System, and Surgical Planning Laboratory, MRI Division, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
出版信息
Schizophr Res. 2003 Nov 1;64(1):35-9. doi: 10.1016/s0920-9964(02)00529-7.
Abstract
The fusiform gyrus is important for face and object recognition, is abnormal in schizophrenia, but has not been studied in schizotypal personality disorder (SPD). Thin-slice MR images showed no differences, either in right, left or total fusiform gyri volumes, between subjects with SPD (N=21) and normal controls (N=19). However, there was a correlation between severity of illusions and magical thinking suffered by the SPD subjects and smaller right fusiform gyrus volumes. This suggests that future studies may be useful in determining the functional competence of this gyrus in SPD.
摘要
梭状回对于面部和物体识别很重要，在精神分裂症中存在异常，但尚未在分裂型人格障碍（SPD）中进行研究。薄层磁共振成像显示，SPD患者（N = 21）和正常对照组（N = 19）在右侧、左侧或整个梭状回体积上均无差异。然而，SPD患者所经历的幻觉和神奇思维的严重程度与右侧梭状回较小的体积之间存在相关性。这表明未来的研究可能有助于确定该脑回在SPD中的功能能力。
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