Heise M, Schmidt S, Krüger U, Pfitzmann R, Scholz H, Neuhaus P, Settmacher U
Department of General Surgery, Humboldt University, Charité, Campus Virchow Klinikum, Berlin, Germany.
Eur J Vasc Endovasc Surg. 2003 Oct;26(4):367-73. doi: 10.1016/s1078-5884(03)00243-0.
To use particle image velocimetry (PIV) to study the haemodynamics and shear stress associated with cuffed and straight PTFE-venous anastomoses.
Silastic models of a straight and cuffed (Venaflo) PTFE-venous anastomoses were attached to a pulsatile flow 'Berlin Heart' circuit filled with glycerine/water and hollow glass tracer spheres. Instantaneous velocity fields were obtained PIV and shear rates and patterns calculated from frame-by-frame analysis.
A high velocity jet struck the anastomotic 'floor' and was deflected toward the venous outflow. Shear stresses near the floor were significantly higher, in the straight anastomosis. Sites of high shear stress correlated well with the known sites of intimal hyperplasia.
A cuffed anastomosis type may be favourable in terms of local haemodynamics so enhancing the long-term patency of PTFE-venous grafts.
使用粒子图像测速技术（PIV）研究带袖口和直管状聚四氟乙烯（PTFE）静脉吻合术相关的血流动力学和剪切应力。
将直管状和带袖口（Venaflo）PTFE静脉吻合术的硅橡胶模型连接到充满甘油/水和空心玻璃示踪球的脉动血流“柏林心脏”循环装置上。通过PIV获得瞬时速度场，并通过逐帧分析计算剪切速率和模式。
高速射流撞击吻合口“底部”并偏向静脉流出方向。在直管状吻合术中，底部附近的剪切应力明显更高。高剪切应力部位与已知的内膜增生部位相关性良好。
就局部血流动力学而言，带袖口的吻合术类型可能更有利，从而提高PTFE静脉移植物的长期通畅率。
