Handfield-Jones S E, Parker S C, Fenton D A, Newton J A, Greaves M W
St. John's Dermatology Centre, St. Thomas's Hospital, London, UK.
Clin Exp Dermatol. 1992 May;17(3):197-200. doi: 10.1111/j.1365-2230.1992.tb00206.x.
We report three cases of Wegener's granulomatosis presenting with cutaneous ulceration resembling pyoderma gangrenosum. Wegener's granulomatosis classically affects the upper and lower respiratory tracts and the kidneys. Skin involvement occurs in up to 50% of patients. Increased awareness that cutaneous involvement can take the form of pyoderma gangrenosum and that it can be a presenting sign may lead to more rapid diagnosis of Wegener's granulomatosis.
我们报告了3例韦格纳肉芽肿病，其表现为类似坏疽性脓皮病的皮肤溃疡。韦格纳肉芽肿病典型地累及上、下呼吸道及肾脏。高达50%的患者会出现皮肤受累。认识到皮肤受累可能表现为坏疽性脓皮病且可能是首发症状，这可能会使韦格纳肉芽肿病得到更快速的诊断。
