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典型失神发作患者的综合征分类。

Syndromic classification of patients with typical absence seizures.

作者信息

Guilhoto Laura M F F, Manreza Maria Luíza G, Yacubian Elza M T

机构信息

Divisão de Clínica Neurológica, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.

出版信息

Arq Neuropsiquiatr. 2003 Sep;61(3A):580-7. doi: 10.1590/s0004-282x2003000400010. Epub 2003 Sep 16.

Abstract

The aim of this study is to compare ILAE classification (1989) and Panayiotopoulos' criteria (1997) for absence epilepsies. We studied 455 typical absences (ILAE, 1981) by video-EEG in 43 patients with normal neurological and neuroradiological examinations and interictal EEG with spike-wave complexes higher than 2.5Hz. Syndromic diagnosis was possible in 60.5% and 67.4% of the patients using ILAE classification and Panayiotopoulos' proposal, respectively. According to ILAE criteria 19 patients had childhood absence epilepsy (CAE), five juvenile absence epilepsy (JAE), one juvenile myoclonic epilepsy (JME) and one epilepsy with specific modes of seizure precipitation. According to Panayiotopoulos' proposal, 10 had CAE, 14 JAE, one JME, three myoclonic absence epilepsy and one eyelid myoclonia with absences. We conclude that Panayiotopoulos' criteria and ILAE classification for absence epilepsies, which did not allow for the classification of 32.6% and 39.5% of cases, respectively, were still insufficient to classify all patients under specific diagnosis.

摘要

本研究旨在比较国际抗癫痫联盟(ILAE,1989年)和帕纳约托普洛斯标准(1997年)对失神癫痫的分类。我们对43例神经学和神经放射学检查正常且发作间期脑电图有高于2.5Hz棘慢复合波的患者进行了视频脑电图检查,研究了455次典型失神发作(ILAE,1981年)。分别采用ILAE分类和帕纳约托普洛斯标准,60.5%和67.4%的患者能够进行综合征诊断。根据ILAE标准,19例患者患有儿童失神癫痫(CAE),5例青少年失神癫痫(JAE),1例青少年肌阵挛癫痫(JME),1例具有特定发作诱发模式的癫痫。根据帕纳约托普洛斯标准,10例患有CAE,14例JAE,1例JME,3例肌阵挛失神癫痫和1例伴有失神的眼睑肌阵挛。我们得出结论,帕纳约托普洛斯标准和ILAE对失神癫痫的分类分别仍不足以对32.6%和39.5%的病例进行分类,仍不足以对所有患者进行特定诊断分类。

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