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儿童期失神发作的短期视频脑电图监测分类及鉴别诊断

The classification and differential diagnosis of absence seizures with short-term video-EEG monitoring during childhood.

作者信息

Uysal-Soyer Ozge, Yalnizoğlu Dilek, Turanli Güzide

机构信息

Pediatric Neurology Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Turk J Pediatr. 2012 Jan-Feb;54(1):7-14.

PMID:22397035
Abstract

Absence seizures are idiopathic epilepsies characterized by impairment of consciousness and generalized 2.5-4 Hz spike and slow wave discharges. This prospective study was performed to classify and define properties of subgroups of absence epilepsies. We included 31 patients, of whom seven were in the differential diagnosis group. On admission, absence epilepsy provisional diagnosis was considered in 16 patients clinically and in the other 15 patients based on routine EEG findings. Ictal EEGs were recorded by video-EEG monitoring in 23 of the patients (totally 202 ictal recordings). Patients were diagnosed as childhood absence epilepsy (n=8), juvenile absence epilepsy (n=10), juvenile myoclonic epilepsy (n=3), eyelid myoclonia with absences (n=2), and perioral myoclonia with absences (n=1). Neuroimaging, video-EEG monitoring and especially ictal recordings are important for classification of epilepsies in addition to history, physical examination and routine EEG findings. Video-EEG monitoring is required to classify, to make differential diagnosis and to determine the treatment plan and prognosis.

摘要

失神发作是一种特发性癫痫,其特征为意识障碍以及全身性2.5 - 4赫兹棘慢波放电。本前瞻性研究旨在对失神癫痫亚组的特性进行分类和界定。我们纳入了31例患者,其中7例在鉴别诊断组。入院时,16例患者临床上被考虑为失神癫痫初步诊断,另外15例基于常规脑电图检查结果被考虑为初步诊断。23例患者通过视频脑电图监测记录了发作期脑电图(共202次发作期记录)。患者被诊断为儿童失神癫痫(n = 8)、青少年失神癫痫(n = 10)、青少年肌阵挛癫痫(n = 3)、伴有失神的眼睑肌阵挛(n = 2)以及伴有失神的口周肌阵挛(n = 1)。除了病史、体格检查和常规脑电图检查结果外,神经影像学、视频脑电图监测尤其是发作期记录对于癫痫的分类很重要。需要视频脑电图监测来进行分类、鉴别诊断以及确定治疗方案和预后。

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