Gauer I C, Hagen V, Merz H
Department of Pathology, University of Schleswig-Holstein, Ratzeburger Allee 160, 23538 Luebeck, Germany.
Ann Hematol. 2004 Apr;83(4):251-2. doi: 10.1007/s00277-003-0754-6. Epub 2003 Sep 26.
We present a 20-year-old man with a rare variant of multiple myeloma with peculiar spindle cell morphology and sarcomatoid growth. The diagnosis of multiple myeloma was substantiated by clinical examinations. The patient was treated with several therapeutic trials including autologous stem cell support. Unfortunately, he developed a disseminated aspergillosis of the lungs and died of fatal lung bleeding. We recommended that "sarcomatous" multiple myeloma be considered in cases of "unclassifiable" sarcomatous tumors of the bone marrow.
我们报告一名20岁男性，患有多发性骨髓瘤的罕见变异型，具有独特的梭形细胞形态和肉瘤样生长方式。多发性骨髓瘤的诊断通过临床检查得以证实。该患者接受了包括自体干细胞支持在内的多项治疗试验。不幸的是，他发生了肺部播散性曲霉病，并死于致命的肺出血。我们建议，在遇到骨髓“无法分类”的肉瘤样肿瘤病例时，应考虑“肉瘤样”多发性骨髓瘤。
