Khosravi Shahi P
Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañon, Madrid.
An Med Interna. 2005 Nov;22(11):532-4.
Plasma cell leukaemia is a rare variant of multiple myeloma (2-3%), with an aggressive disease with short survival. It is defined as circulating peripheral blood plasma cells exceeding 2.000/ul and 20% of peripheral blood white cells. We present the case of 32-years-old man with left chest-wall pain, hepatomegaly, righ cervical adenopathy, 8800 leukocytes/ul with 33% of lymphocytes and 40% of plasma cell, 10.8 g/dl of proteins and a monoclonal hypergammaglobulinemia. Bone marrow biopsy showed 40-50 % of intramedullary plasma cell. There was a Ig G-kappa paraproteinemia.
浆细胞白血病是多发性骨髓瘤的一种罕见变异型（2%-3%），是一种侵袭性疾病，生存期短。它被定义为循环外周血浆细胞超过2000/微升且占外周血白细胞的20%。我们报告一例32岁男性病例，患者有左胸壁疼痛、肝肿大、右颈部淋巴结病，白细胞计数为8800/微升，其中淋巴细胞占33%，浆细胞占40%，蛋白水平为10.8克/分升，存在单克隆高丙种球蛋白血症。骨髓活检显示骨髓内浆细胞占40%-50%。存在IgG-κ型副蛋白血症。
