Zhou Wen-Quan, Gao Jian-Ping, Wu Bo, Zhou Shui-Sheng
Department of Urology, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
Zhonghua Nan Ke Xue. 2003 Aug;9(5):389-90.
Papillary cystadenoma of the epididymis is a rare benign tumor, accounting for only 4 per cent of all epididymal tumors. Histologically, it can be confused with metastatic renal cell carcinoma. This extremely rare lesion may occur sporadically or as a manifestation of von Hippel-Lindau(VHL) disease. The present paper reported a case of papillary cystadenoma accompanied by testicular atrophy with no signs of VHL syndrome or infertility. To date, no similar case was reported in the literature. The tumor measured 5.0 cm x 4.0 cm x 4.0 cm and was located in the right epididymis. Histopathologic examination of a surgically removed specimen indicated a primary papillary cystadenoma. Histomorphologically, these tumors are characterized by cysts with colloid-like contents and papillary formations of light epithelium. Since metastatic renal cell carcinoma may be histologically similar to papillary cystadenoma, the importance of long-term urologic follow-up for possible presentation of renal cell carcinoma is discussed.
附睾乳头状囊腺瘤是一种罕见的良性肿瘤，仅占所有附睾肿瘤的4%。在组织学上，它可能与转移性肾细胞癌混淆。这种极其罕见的病变可能散发性出现，或作为冯·希佩尔-林道（VHL）病的一种表现。本文报告了一例伴有睾丸萎缩的乳头状囊腺瘤病例，无VHL综合征或不育迹象。迄今为止，文献中未报道过类似病例。肿瘤大小为5.0 cm×4.0 cm×4.0 cm，位于右侧附睾。对手术切除标本的组织病理学检查显示为原发性乳头状囊腺瘤。在组织形态学上，这些肿瘤的特征是含有胶样内容物的囊肿和轻度上皮的乳头状结构。由于转移性肾细胞癌在组织学上可能与乳头状囊腺瘤相似，因此讨论了对可能出现的肾细胞癌进行长期泌尿外科随访的重要性。
